Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tfap2a  transcription factor AP-2, alpha   (Synonyms: Ap2, Ap-2 (a), AP2alpha, AP-2 alpha, Ap2tf, Tcfap2a)
Results	Reference
1	J:245045 Aghajanian H, Cho YK, Rizer NW, Wang Q, Li L, Degenhardt K, Jain R, Pdgfralpha functions in endothelial-derived cells to regulate neural crest cells and the development of the great arteries. Dis Model Mech. 2017 Sep 01;10(9):1101-1108
1*	J:205268 Ahmad N, Aslam M, Muenster D, Horsch M, Khan MA, Carlsson P, Beckers J, Graw J, Pitx3 directly regulates Foxe3 during early lens development. Int J Dev Biol. 2013;57(9-10):741-51
1*	J:231312 Baardman ME, Zwier MV, Wisse LJ, Gittenberger-de Groot AC, Kerstjens-Frederikse WS, Hofstra RM, Jurdzinski A, Hierck BP, Jongbloed MR, Berger RM, Plosch T, DeRuiter MC, Common arterial trunk and ventricular non-compaction in Lrp2 knockout mice indicate a crucial role of LRP2 in cardiac development. Dis Model Mech. 2016 Apr 1;9(4):413-25
1	J:158712 Bassett EA, Williams T, Zacharias AL, Gage PJ, Fuhrmann S, West-Mays JA, AP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis. Hum Mol Genet. 2010 May 1;19(9):1791-804
1	J:204657 Forni PE, Bharti K, Flannery EM, Shimogori T, Wray S, The indirect role of fibroblast growth factor-8 in defining neurogenic niches of the olfactory/GnRH systems. J Neurosci. 2013 Dec 11;33(50):19620-34
1	J:171903 Forni PE, Taylor-Burds C, Melvin VS, Williams T, Wray S, Neural Crest and Ectodermal Cells Intermix in the Nasal Placode to Give Rise to GnRH-1 Neurons, Sensory Neurons, and Olfactory Ensheathing Cells. J Neurosci. 2011 May 4;31(18):6915-27
1	J:252092 Gard C, Gonzalez Curto G, Frarma YE, Chollet E, Duval N, Auzie V, Aurade F, Vigier L, Relaix F, Pierani A, Causeret F, Ribes V, Pax3- and Pax7-mediated Dbx1 regulation orchestrates the patterning of intermediate spinal interneurons. Dev Biol. 2017 Dec 1;432(1):24-33
1	J:69286 Haack H, Hynes RO, Integrin receptors are required for cell survival and proliferation during development of the peripheral glial lineage. Dev Biol. 2001 May 1;233(1):38-55
1	J:214344 Kerr CL, Zaveri MA, Robinson ML, Williams T, West-Mays JA, AP-2alpha is required after lens vesicle formation to maintain lens integrity. Dev Dyn. 2014 Oct;243(10):1298-309
1*	J:63183 Kramer PR, Guerrero G, Krishnamurthy R, Mitchell PJ, Wray S, Ectopic expression of luteinizing hormone-releasing hormone and peripherin in the respiratory epithelium of mice lacking transcription factor AP-2alpha. Mech Dev. 2000 Jun;94(1-2):79-94
1	J:209623 Kurosaka H, Iulianella A, Williams T, Trainor PA, Disrupting hedgehog and WNT signaling interactions promotes cleft lip pathogenesis. J Clin Invest. 2014 Apr 1;124(4):1660-71
1	J:240081 Mayeuf-Louchart A, Montarras D, Bodin C, Kume T, Vincent SD, Buckingham M, Endothelial cell specification in the somite is compromised in Pax3-positive progenitors of Foxc1/2 conditional mutants, with loss of forelimb myogenesis. Development. 2016 Mar 01;143(5):872-9
1*	J:344235 Nguyen TT, Mitchell JM, Kiel MD, Kenny CP, Li H, Jones KL, Cornell RA, Williams TJ, Nichols JT, Van Otterloo E, TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway. Development. 2024 Jan 1;151(1):dev202095
1*	J:306393 Ofek S, Wiszniak S, Kagan S, Tondl M, Schwarz Q, Kalcheim C, Notch signaling is a critical initiator of roof plate formation as revealed by the use of RNA profiling of the dorsal neural tube. BMC Biol. 2021 Apr 23;19(1):84
1	J:341389 Ong ALC, Kokaji T, Kishi A, Takihara Y, Shinozuka T, Shimamoto R, Isotani A, Shirai M, Sasai N, Acquisition of neural fate by combination of BMP blockade and chromatin modification. iScience. 2023 Oct 20;26(10):107887
1	J:266206 Peterson JC, Chughtai M, Wisse LJ, Gittenberger-de Groot AC, Feng Q, Goumans MTH, VanMunsteren JC, Jongbloed MRM, DeRuiter MC, Nos3 mutation leads to abnormal neural crest cell and second heart field lineage patterning in bicuspid aortic valve formation. Dis Model Mech. 2018 Sep 20;:dmm034637
1	J:204680 Sugiyama Y, Shelley EJ, Wen L, Stump RJ, Shimono A, Lovicu FJ, McAvoy JW, Sfrp1 and Sfrp2 are not involved in Wnt/beta-catenin signal silencing during lens induction but are required for maintenance of Wnt/beta-catenin signaling in lens epithelial cells. Dev Biol. 2013 Dec 15;384(2):181-93
1*	J:277247 Vetrivel S, Tiso N, Kugler A, Irmler M, Horsch M, Beckers J, Hladik D, Giesert F, Gailus-Durner V, Fuchs H, Sabrautzki S, Adler T, Treise I, Busch DH, Aguilar-Pimentel A, Ollert M, Gotz A, Amarie OV, Stoeger T, Schulz H, Becker L, Klopstock T, Schrewe A, Spielmann N, Bekeredjian R, Garrett L, Holter SM, Zimprich A, Wurst W, Mayer-Kuckuk P, Hans W, Rozman J, Klingenspor M, Neff F, da Silva-Buttkus P, Calzada-Wack J, Racz I, Zimmer A, Rathkolb B, Wolf E, Prehn C, Adamski J, Ostereicher M, Miller G, Steinkamp R, Lengger C, Maier H, Stoeger C, Leuchtenberger S, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Hrabe de Angelis M, Graw J, Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia. Exp Eye Res. 2019 Apr 13;
1	J:279272 Wang JJ, Liu HX, Song L, Li HR, Yang YP, Zhang T, Jing Y, Isl-1 positive pharyngeal mesenchyme subpopulation and its role in the separation and remodeling of the aortic sac in embryonic mouse heart. Dev Dyn. 2019 Sep;248(9):771-783
1	J:304634 Watanabe Y, Seya D, Ihara D, Ishii S, Uemoto T, Kubo A, Arai Y, Isomoto Y, Nakano A, Abe T, Shigeta M, Kawamura T, Saito Y, Ogura T, Nakagawa O, Importance of endothelial Hey1 expression for thoracic great vessel development and its distal enhancer for Notch-dependent endothelial transcription. J Biol Chem. 2020 Dec 18;295(51):17632-17645
1	J:116994 Winseck AK, Oppenheim RW, An in vivo analysis of Schwann cell programmed cell death in embryonic mice: the role of axons, glial growth factor, and the pro-apoptotic gene Bax. Eur J Neurosci. 2006 Oct;24(8):2105-17
1	J:184697 Zhao J, Kawai K, Wang H, Wu D, Wang M, Yue Z, Zhang J, Liu YH, Loss of Msx2 Function Down-Regulates the FoxE3 Expression and Results in Anterior Segment Dysgenesis Resembling Peters Anomaly. Am J Pathol. 2012 Jun;180(6):2230-9